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Stop Dying EarlySignal Check

Mogire Cardiac Risk Audit

How is SDE different from Function Health, InsideTracker, or Lifeforce?

Evidence rating

Function Health, InsideTracker, and Lifeforce are excellent tools for what they do: generating extensive biomarker panels and providing AI-generated or algorithm-driven interpretation. They are not staffed by practicing cardiologists. Their strength is full lab coverage and trend tracking over time. Their gap is the interpretive layer that requires a physician who has been in the cardiac catheterization lab, who recognizes the specific combination of ApoB 145 + Lp(a) 88 + hs-CRP 2.9 as a clinical pattern rather than three independent flagged values, and who can tell you what that pattern means for the decade ahead.

A Function Health report that flags an ApoB of 161 as "elevated" is accurate. It cannot tell you whether your ApoB of 161 in the context of your specific Lp(a), hs-CRP, family history, and home blood pressure pattern represents a situation where statin therapy should start immediately or one where dietary optimization for 90 days is the appropriate first step. That judgment requires the cardiologist's pattern recognition and the clinical authority to make a specific recommendation. SDE provides that layer on top of whatever data you bring.

What to do: Function Health and InsideTracker are useful for generating the data. SDE is useful for reading it in cardiovascular context. They are complementary, not competing.

For the full picture, read The Mogire Cardiac Risk Audit.

Deep Dive

For the full clinical picture: Read the full essay →

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